The Adipose were introduced in Series 4 of Doctor Who with David Tennant in the seasons opening episode "Partners in Crime".

Their breeding world was lost, causing them to turn to the alien "Miss Foster" to create a new generation; she created a drug that would cause human fat (anatomically: 'adipose tissue') to parthenogenetically create baby Adipose, although they can convert bone, hair and muscle tissue in emergency circumstances (but making them ill). Ten thousand were spawned. The official Doctor Who website's Monster Files feature states that the baby Adipose were taken into care by the Shadow Proclamation.

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